Consequences of early postnatal benzodiazepines exposure in rats. II. Social behavior
نویسندگان
چکیده
منابع مشابه
Consequences of early postnatal benzodiazepines exposure in rats. II. Social behavior
Social behavior represents an integral part of behavioral repertoire of rats particularly sensitive to pharmacological and environmental influences. The aim of the present study was to investigate whether early postnatal clonazepam (CZP) exposure can induce age-dependent changes related to expression of social behavior. The drug was administered from postnatal day (P) 7 until P11 at daily doses...
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Clinical and experimental studies suggest possible risks associated with the repeated administration of benzodiazepines (BZDs) during the prenatal or early postnatal period on further development and behavior. In the present study, we assess short- and long-term effects of early exposure to clonazepam (CZP) on cognitive tasks. CZP (0.5 or 1.0 mg/kg/day) was administered from postnatal day (P)7 ...
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s | 27 Results: Social defeat stress as juveniles, even with 1-day exposure, induced robust and persistent deficits of social behaviors in relation to the unfamiliar ICR mouse, compared with the responses of mice exposed to the stress as adults. The stress did not affect anxiety-like behaviors during spontaneous locomotor activity in a novel environment and performance on the elevated plus-maze...
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ژورنال
عنوان ژورنال: Frontiers in Behavioral Neuroscience
سال: 2014
ISSN: 1662-5153
DOI: 10.3389/fnbeh.2014.00169